Animal Phenotyping Core

The Animal Phenotyping Core (APC) enables investigators to efficiently and cost effectively define the phenotypes of small rodents in ways that are relevant to the study of obesity, nutrition, and metabolism. The phenotyping capabilities of the APC range from whole animal measurements of body composition and energy utilization, to ex vivo measurements of substrate fluxes, to histological analyses of adipose tissue. In addition to the service provided, the APC provides expertise to guide both new and experienced investigators in the selection and use of techniques to define metabolic and related phenotypes.

Services

Adipose Tissue Morphology & Function Energy Intake & Expenditure Body Composition Analysis Metabolic Surgery

Histologic and Morphometric Analysis

Indirect calorimetry plus food intake

Body Composition in Conscious Animals – MRI Analysis

Bariatric Surgery

Primary Cell Isolation and Analysis

Feeding behavior

Body Composition and Bone Density – DEXA Analysis

Autonomic denervations

Differentiation of Adipocytes and Adipose Tissue Macrophages

Exercise calorimetry

Body Composition and Distribution - MicroCT Analysis

Gastrointestinal tube feeding

Metabolic Function of Adipose Tissue

Temperature challenge and core body temperature measurements

 

Stereotactic brain cannulations & injections

Adipose Tissue Transplantation

 

 

Bone marrow transplantation

Forms

Personnel

  • Yiying Zhang, PhD

    Associate Director

  • Anthony Ferrante Jr. MD, PhD

    Associate Director

  • Kaiying Guo, BS

    Technician

  • Licheng Wu, MA

    Technician

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