Animal Phenotyping Core

The Animal Phenotyping Core (APC) enables investigators to efficiently and cost effectively define the phenotypes of small rodents in ways that are relevant to the study of obesity, nutrition, and metabolism. The phenotyping capabilities of the APC range from whole animal measurements of body composition and energy utilization, to ex vivo measurements of substrate fluxes, to histological analyses of adipose tissue. In addition to the service provided, the APC provides expertise to guide both new and experienced investigators in the selection and use of techniques to define metabolic and related phenotypes.

Services

Adipose Tissue Morphology & Function	Energy Intake & Expenditure	Body Composition Analysis	Metabolic Surgery
Histologic and Morphometric Analysis	Indirect calorimetry plus food intake	Body Composition in Conscious Animals – MRI Analysis	Bariatric Surgery
Primary Cell Isolation and Analysis	Feeding behavior	Body Composition and Bone Density – DEXA Analysis	Autonomic denervations
Differentiation of Adipocytes and Adipose Tissue Macrophages	Exercise calorimetry	Body Composition and Distribution - MicroCT Analysis	Gastrointestinal tube feeding
Metabolic Function of Adipose Tissue	Temperature challenge and core body temperature measurements		Stereotactic brain cannulations & injections
Adipose Tissue Transplantation			Bone marrow transplantation