Charles Zuker, PhD

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Overview

Academic Appointments

  • Professor of Biochemistry and Molecular Biophysics
  • Professor of Neuroscience

Gender

  • Male

Research

The senses of vision, hearing, touch, olfaction, and taste have the critical roles of providing the organism with a faithful representation of the external world. We use a combined molecular, genetic, and physiological approach to investigate the biology of sensory transduction in various systems and model organisms.

Research Interests

  • Brain Imaging
  • Sensory Physiology
  • Neurogenetics
  • Synapses and Circuits

Grants

THE REWARDING VALUE OF SUGAR IN THE ABSENCE OF SWEET TASTE (Federal Gov)

Sep 1 2015 - Aug 31 2020

2016 PEW LATIN AMERICAN FELLOWS PROGRAM IN THE BIOMEDICAL SCIENCES (Private)

Aug 1 2016 - Jul 31 2020

BRAIN CIRCUITS MEDIATING MOTIVATED BEHAVIORS (Federal Gov)

Jan 1 2013 - Dec 31 2018

GFP RECONSTITUTION ACROSS SYNAPTIC PARTNERS (GRASP) METHODS TO DISSECT MAMMALIAN NEURAL CIRCUITS (Federal Gov)

Sep 1 2011 - May 31 2016

MAMMALIAM TASTE CELLS DIFFERENTIATION RENEWAL AND MAINTENANCE (Private)

Nov 1 2009 - Oct 31 2013

PEDICATRIC SCIENTIST DEVELOPMENT PROGRAM (Federal Gov)

Jul 3 2012 - Jun 30 2013

NEURONAL ASPECTS OF ASTHMA (Private)

Dec 1 2009 - Jun 30 2013

VALIDATING GFP RECONSTITUTION ACROSS SYNAPTIC PARTNERS (GRAS P) METHODS TO DISSECT (Federal Gov)

Sep 30 2009 - Aug 31 2011

SUPPORT FOR VERONICA PALMA (Private)

Jul 1 2010 - Mar 31 2011

Selected Publications

Selected

  • Chandrashekar, J., et al (2010). The cells and peripheral representation of sodium taste in mice. Nature 464: 297-301.
  • Yarmolinsky, D., C.S. Zuker, and N.J.P. Ryba (2009) Common Sense about Taste: From Mammals to Insects. Cell 139: 234-244.
  • Chandrashekar, J., et al. (2009). The taste of carbonation. Science 326: 443-445.
  • Cook, B., R.W. Hardy, W.B. McConnaughey and C.S. Zuker (2008). Preserving cell shape under environmental stress. Nature 452: 361-364.
  • Chandrashekar, J, M.A. Hoon, N.J.P. Ryba and C.S. Zuker (2006). The receptors and cells for mammalian taste. Nature 444: 288-294.
  • Zelhof, A.C., R.W. Hardy, A. Becker and C.S. Zuker (2006). Transforming the architecture of compound eyes. Nature 443: 696-699.
  • Huang, A.L., X. Chen, M.A. Hoon, J. Chandrashekar, W. Guo, D. Tr√§nkner, N.J.P. Ryba and C.S. Zuker (2006). The cells and logic for mammalian sour taste detection. Nature 442: 934-938.
  • Mueller, K.L., M.A. Hoon, I. Erlenbach, J. Chandrashekar, C.S. Zuker and N.J.P. Ryba (2005). The receptors and coding logic for bitter taste. Nature 434: 225-229.
  • Zhao, G.Q., Y. Zhang, M.A. Hoon, J. Chandrashekar, I. Erlenbach, N.J.P. Ryba and C.S. Zuker (2003). The receptors for mammalian sweet and umami taste. Cell, 115: 255-266.