Animal Phenotyping Core

The Animal Phenotyping Core (APC) enables investigators to efficiently and cost effectively define the phenotypes of small rodents in ways that are relevant to the study of obesity, nutrition, and metabolism. The phenotyping capabilities of the APC range from whole animal measurements of body composition and energy utilization, to ex vivo measurements of substrate fluxes, to histological analyses of adipose tissue. In addition to the service provided, the APC provides expertise to guide both new and experienced investigators in the selection and use of techniques to define metabolic and related phenotypes.

Services

Adipose Tissue Morphology & Function Energy Intake & Expenditure Body Composition Analysis Metabolic Surgery
  • Histologic and Morphometric Analysis
  • Indirect calorimetry plus food intake
  • Body Composition in Conscious Animals – MRI Analysis
  • Bariatric Surgery
  • Primary Cell Isolation and Analysis
  • Feeding behavior
  • Body Composition and Bone Density – DEXA Analysis
  • Autonomic denervations
  • Differentiation of Adipocytes and Adipose Tissue Macrophages
  • Exercise calorimetry
  • Body Composition and Distribution - MicroCT Analysis
  • Gastrointestinal tube feeding
  • Metabolic Function of Adipose Tissue
  • Temperature challenge and core body temperature measurements
 
  • Stereotactic brain cannulations & injections
  • Adipose Tissue Transplantation
   
  • Bone marrow transplantation

Forms

Personnel

  • Yiying Zhang, PhD

    Associate Director

  • Anthony Ferrante Jr. MD, PhD

    Associate Director

  • Kaiying Guo, BS

    Technician

  • Licheng Wu, MA

    Technician

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